Tspan3 Gene Summary [Rat]
Predicted to be active in plasma membrane. Orthologous to human TSPAN3 (tetraspanin 3). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tspan3 |
| Official Name | tetraspanin 3 [Source:RGD Symbol;Acc:1359444] |
| Ensembl ID | ENSRNOG00000016474 |
| Bio databases IDs | |
| Aliases | tetraspanin 3 |
| Synonyms | 1700055K04Rik, Tetraspanin 3, TM4-A, TM4SF8 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tspan3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- tetraspanin_LEL
- Tetraspanin family
Pathways
Biological processes and signaling networks where the Tspan3 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-insulin-dependent diabetes mellitus
- chronic obstructive pulmonary disease
- nonalcoholic steatohepatitis
- coronary artery disease
role in cell
- proliferation
- migration
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Tspan3 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- plasma membrane