Chpf2 Gene Summary [Rat]

Predicted to enable glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. Predicted to be involved in chondroitin sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi cisterna membrane. Predicted to be active in Golgi apparatus. Orthologous to human CHPF2 (chondroitin polymerizing factor 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Chpf2
Official Name
chondroitin polymerizing factor 2 [Source:RGD Symbol;Acc:1306404]
Ensembl ID
ENSRNOG00000010466
Bio databases IDs NCBI: 296733 Ensembl: ENSRNOG00000010466
Aliases chondroitin polymerizing factor 2
Synonyms 2010209O12Rik, chondroitin polymerizing factor 2, CHONDROITIN SULFATE GLUCURONYLTRANSFERASE, CHONDROITIN sulphATE GLUCURONYLTRANSFERASE, ChSy-3, CSGLCA-T, Gm42230, KIAA1402, mir-671, mKIAA1402, RGD1306404
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Chpf2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase
  • Chondroitin N-acetylgalactosaminyltransferase
  • enzyme

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • plasma cell myeloma
  • light chain associated amyloidosis
  • aortic valve calcification
regulated by
  • KLF6
  • MYCN
  • OSW-1
  • heat-killed candida albicans

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • Golgi Apparatus
  • Golgi membrane
  • Golgi stacks

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Chpf2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • chondroitin sulfate biosynthetic process

Cellular Component

Where in the cell the gene product is active
  • Golgi cisterna membrane
  • membrane
  • Golgi membrane

Molecular Function

What the gene product does at the molecular level
  • N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity
  • glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.