Tgoln2 Gene Summary [Rat]
Predicted to be involved in Golgi to endosome transport. Located in trans-Golgi network. Is active in glutamatergic synapse and postsynaptic Golgi apparatus. Orthologous to human TGOLN2 (trans-golgi network protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tgoln2 |
| Official Name | trans-golgi network protein 2 [Source:RGD Symbol;Acc:620445] |
| Ensembl ID | ENSRNOG00000014617 |
| Bio databases IDs | |
| Aliases | trans-golgi network protein 2 |
| Synonyms | Gmpt1, hTGN46, hTGN48, hTGN51, TGN38, TGN38B, TGN41, TGN46, TGN51, Tgoln1, trans-golgi network protein 2, Ttgn1, TTGN2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tgoln2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- internalization targeting signal
- endocytic signal motif
- Keratinocyte-associated gene product
- cytoplasmic domain
- protein binding
- cytosolic tail domain
- sorting signal domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- soluble fraction
- glutaminergic synapse
- endocytic vesicle membrane
- cell surface
- perinuclear region
- cellular membrane
- Golgi apparatus component
- Plasma Membrane
- endosomes
- vesicles
- Golgi Apparatus
- endoplasmic reticulum lumen
- Golgi membrane
- trans face of the Golgi apparatus
- trans Golgi network
- nucleoplasm
- perinuclear space
- spine apparatus
- myofibrils
- transport vesicles
- Golgi cisternae
- perikaryon
- dendrites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Tgoln2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum lumen
- trans-Golgi network
- clathrin-coated endocytic vesicle membrane
- endosome
- trans-Golgi network transport vesicle
- Golgi apparatus
- transport vesicle
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding