LOC299282 Gene Summary [Rat]
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in response to cytokine. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease; cystic fibrosis; and vasculitis. Orthologous to human SERPINA3 (serpin family A member 3). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | LOC299282 |
| Official Name | Serine protease inhibitor [Source:RGD Symbol;Acc:3745] |
| Ensembl ID | ENSRNOG00000010478 |
| Bio databases IDs | |
| Aliases | Serine protease inhibitor |
| Synonyms | Ab1-021, Contrapsin-like protease inhibitor 3, CPi-23, serine (or cysteine) peptidase inhibitor, clade A, member 3L, Serpin2a, SPI1, Spi2-1, Spi2.1, Spin1, Spin2a |
| Species | Rat, Rattus norvegicus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Loc299282 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SERine Proteinase INhibitors (serpin) family
- Serpin (serine protease inhibitor)
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space