Kif6 Gene Summary [Rat]
Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in spermatogenesis. Located in male germ cell nucleus. Human ortholog(s) of this gene implicated in artery disease (multiple) and type 2 diabetes mellitus. Orthologous to human KIF6 (kinesin family member 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kif6 |
| Official Name | kinesin family member 6 [Source:RGD Symbol;Acc:621070] |
| Ensembl ID | ENSRNOG00000011453 |
| Bio databases IDs | |
| Aliases | kinesin family member 6 |
| Synonyms | C6ORF102, D130004B10Rik, D130084M03, D130084M03Rik, dJ1043E3.1, dJ137F1.4, dJ188D3.1, kinesin family member 6, KRP3 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Kif6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Kinesin motor, catalytic domain
- microtubule binding
- Myosin and Kinesin motor domain
- Kinesin motor domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Kif6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- microtubule-based movement
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- kinesin complex
- microtubule
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- microtubule motor activity
- protein binding
- microtubule binding