Kif6 Gene Summary [Mouse]
Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement. Predicted to be located in male germ cell nucleus. Predicted to be part of kinesin complex. Predicted to be active in cytoplasm and microtubule. Is expressed in lateral ventricle choroid plexus and metencephalon part of 4th ventricle choroid plexus. Human ortholog(s) of this gene implicated in artery disease (multiple) and type 2 diabetes mellitus. Orthologous to human KIF6 (kinesin family member 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Kif6 |
| Official Name | kinesin family member 6 [Source:MGI Symbol;Acc:MGI:1098238] |
| Ensembl ID | ENSMUSG00000023999 |
| Bio databases IDs | |
| Aliases | kinesin family member 6 |
| Synonyms | C6ORF102, D130004B10Rik, D130084M03, D130084M03Rik, dJ1043E3.1, dJ137F1.4, dJ188D3.1, kinesin family member 6, KRP3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kif6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Kinesin motor, catalytic domain
- microtubule binding
- Myosin and Kinesin motor domain
- Kinesin motor domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Kif6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- microtubule-based movement
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- kinesin complex
- microtubule
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- microtubule motor activity
- protein binding
- microtubule binding