Itpripl1 Gene Summary [Rat]
Predicted to enable receptor ligand activity. Predicted to be involved in negative regulation of T cell receptor signaling pathway. Predicted to act upstream of or within T cell differentiation; calcium ion import; and protein phosphorylation. Predicted to be active in plasma membrane. Orthologous to human ITPRIPL1 (ITPRIP like 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Itpripl1 |
| Official Name | ITPRIP like 1 [Source:RGD Symbol;Acc:1564158] |
| Ensembl ID | ENSRNOG00000012151 |
| Bio databases IDs | |
| Aliases | ITPRIP like 1 |
| Synonyms | 1700041B20Rik, D1B, inositol 1,4,5-triphosphate receptor interacting protein-like 1, ITPRIP like 1, KIAA1754L |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Itpripl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mab-21 protein HhH/H2TH-like domain
- receptor agonist activity
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Itpripl1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding