Itpripl1 Gene Summary [Mouse]

Predicted to enable receptor ligand activity. Acts upstream of or within T cell differentiation; calcium ion import; and protein phosphorylation. Predicted to be located in plasma membrane. Predicted to be active in membrane. Orthologous to human ITPRIPL1 (ITPRIP like 1). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Itpripl1
Official Name
inositol 1,4,5-triphosphate receptor interacting protein-like 1 [Source:MGI Symbol;Acc:MGI:1920588]
Ensembl ID
ENSMUSG00000074825
Bio databases IDs NCBI: 73338 Ensembl: ENSMUSG00000074825
Aliases inositol 1,4,5-triphosphate receptor interacting protein-like 1
Synonyms 1700041B20Rik, D1B, inositol 1,4,5-triphosphate receptor interacting protein-like 1, ITPRIP like 1, KIAA1754L
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Itpripl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Mab-21 protein HhH/H2TH-like domain
  • receptor agonist activity
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diabetic nephropathy
  • breast cancer
regulated by
  • dBET6
role in cell
  • differentiation
  • activation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Itpripl1 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.