LOC100294508 Gene Summary [Rat]

Predicted to be involved in neuron migration. Predicted to act upstream of or within several processes, including flagellated sperm motility; proacrosomal vesicle fusion; and receptor-mediated endocytosis of virus by host cell. Predicted to be located in nucleolus and trans-Golgi network. Predicted to be active in Golgi apparatus; cytoplasmic vesicle; and membrane. Orthologous to human KIAA0319L (KIAA0319 like). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
LOC100294508
Official Name
dyslexia susceptibility 2-like [Source:RGD Symbol;Acc:2306719]
Ensembl ID
ENSRNOG00000012204
Bio databases IDs NCBI: 100294508 Ensembl: ENSRNOG00000012204
Aliases dyslexia susceptibility 2-like
Synonyms A730047D20Rik, AAVR, AAVRL, AU040320, expressed sequence AU040320, KIAA0319 like
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Loc100294508 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • PKD domain
  • REJ domain
  • Cadherin repeat-like domain
  • protein binding
  • Bacterial Ig-like domain
  • Repeats in polycystic kidney disease 1 (PKD1) and other proteins
  • EGF_CA

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insomnia
  • insulin-dependent diabetes mellitus
  • systemic sclerosis
  • systemic lupus erythematosus
role in cell
  • motility
  • migration
  • assembly

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi Apparatus
  • trans Golgi network
  • nucleoli
  • cytoplasmic vesicles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Loc100294508 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • neuron migration

Cellular Component

Where in the cell the gene product is active
  • membrane
  • cytoplasmic vesicle
  • Golgi membrane
  • Golgi apparatus
  • nucleolus
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.