Lgsn Gene Summary [Rat]

Predicted to enable glutamine synthetase activity. Predicted to be involved in glutamine biosynthetic process. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm and membrane. Orthologous to human LGSN (lengsin, lens protein with glutamine synthetase domain). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Lgsn
Official Name
lengsin, lens protein with glutamine synthetase domain [Source:RGD Symbol;Acc:727925]
Ensembl ID
ENSRNOG00000012205
Bio databases IDs NCBI: 316304 Ensembl: ENSRNOG00000012205
Aliases lengsin, lens protein with glutamine synthetase domain
Synonyms GLULD1, LENGSIN, lengsin, lens protein with glutamine synthetase domain, LGS
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Lgsn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Glutamine synthetase, beta-Grasp domain
  • Glutamine synthetase, catalytic domain
  • enzyme
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diabetic nephropathy
  • tuberculosis
  • exfoliative glaucoma
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Lgsn gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • nitrogen utilization
  • glutamine biosynthetic process

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • glutamate-ammonia ligase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.