Lgsn Gene Summary [Mouse]
Predicted to enable glutamine synthetase activity. Predicted to be involved in glutamine biosynthetic process. Located in plasma membrane. Orthologous to human LGSN (lengsin, lens protein with glutamine synthetase domain). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lgsn |
| Official Name | lengsin, lens protein with glutamine synthetase domain [Source:MGI Symbol;Acc:MGI:2672844] |
| Ensembl ID | ENSMUSG00000050217 |
| Bio databases IDs | |
| Aliases | lengsin, lens protein with glutamine synthetase domain |
| Synonyms | GLULD1, LENGSIN, lengsin, lens protein with glutamine synthetase domain, LGS |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lgsn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Glutamine synthetase, beta-Grasp domain
- Glutamine synthetase, catalytic domain
- enzyme
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Lgsn gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nitrogen utilization
- glutamine biosynthetic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- glutamate-ammonia ligase activity