Trmt10b Gene Summary [Rat]
Predicted to enable tRNA (guanosine(9)-N1)-methyltransferase activity and tRNA binding activity. Predicted to be involved in protein insertion into mitochondrial inner membrane and tRNA N1-guanine methylation. Predicted to be located in cytosol and mitochondrial inner membrane. Predicted to be part of TIM22 mitochondrial import inner membrane insertion complex. Predicted to be active in nucleoplasm. Orthologous to human TRMT10B (tRNA methyltransferase 10B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Trmt10b |
| Official Name | tRNA methyltransferase 10B [Source:RGD Symbol;Acc:1310735] |
| Ensembl ID | ENSRNOG00000012454 |
| Bio databases IDs | |
| Aliases | tRNA methyltransferase 10B |
| Synonyms | 2610042J10Rik, bA3J10.9, RG9MTD3, Rnmtd3, tRNA methyltransferase 10B |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Trmt10b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- tRNA (guanine) methyltransferase
- SPOUT superfamily of SAM-dependent RNA methyltransferases
- enzyme
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Trmt10b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein import into mitochondrial inner membrane
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
- mitochondrial inner membrane
- mitochondrial inner membrane protein insertion complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- tRNA (guanine(9)-N(1))-methyltransferase activity
- tRNA binding