Mrps2 Gene Summary [Rat]

Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial ribosome assembly. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial small ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 36. Orthologous to human MRPS2 (mitochondrial ribosomal protein S2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mrps2
Official Name
mitochondrial ribosomal protein S2 [Source:RGD Symbol;Acc:1309116]
Ensembl ID
ENSRNOG00000010164
Bio databases IDs NCBI: 362094 Ensembl: ENSRNOG00000010164
Aliases mitochondrial ribosomal protein S2
Synonyms 1500019M10RIK, CGI-91, COXPD36, mitochondrial ribosomal protein S2, S2mt, uS2m
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mrps2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • structural constituent of ribosome
  • Ribosomal protein S2
  • RPS2

Pathways

Biological processes and signaling networks where the Mrps2 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • combined oxidative phosphorylation deficiency 36
regulated by
  • TP53
  • TO-901317
  • beta-estradiol
  • valproic acid

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial matrix
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mrps2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrial translation

Cellular Component

Where in the cell the gene product is active
  • mitochondrial matrix
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • structural constituent of ribosome

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.