TRMT10B Gene Summary [Human]

Enables tRNA (guanine-N1-)-methyltransferase activity. Predicted to be involved in mitochondrial tRNA processing. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
TRMT10B
Official Name
tRNA methyltransferase 10B [Source:HGNC Symbol;Acc:HGNC:26454]
Ensembl ID
ENSG00000165275
Bio databases IDs NCBI: 158234 Ensembl: ENSG00000165275
Aliases tRNA methyltransferase 10B
Synonyms 2610042J10Rik, bA3J10.9, RG9MTD3, Rnmtd3, tRNA methyltransferase 10B
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TRMT10B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • tRNA (guanine) methyltransferase
  • SPOUT superfamily of SAM-dependent RNA methyltransferases
  • enzyme
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • tetrachlorodibenzodioxin
regulates
  • magnesium

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TRMT10B gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein import into mitochondrial inner membrane

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytosol
  • mitochondrial inner membrane
  • mitochondrial inner membrane protein insertion complex
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • tRNA (guanine(9)-N(1))-methyltransferase activity
  • tRNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.