Uevld Gene Summary [Rat]
Predicted to enable ubiquitin binding activity. Predicted to be involved in endosome to lysosome transport. Predicted to be part of ESCRT I complex. Orthologous to human UEVLD (UEV and lactate/malate dehyrogenase domains). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Uevld |
| Official Name | UEV and lactate/malate dehyrogenase domains [Source:RGD Symbol;Acc:1587416] |
| Ensembl ID | ENSRNOG00000013624 |
| Bio databases IDs | |
| Aliases | UEV and lactate/malate dehyrogenase domains |
| Synonyms | 8430408E05RIK, ATTP, LOC688000, UEV3, UEV and lactate/malate dehyrogenase domains |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Uevld often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rossmann-fold NAD(P)(+)-binding proteins
- L-lactate dehydrogenase
- lactate/malate dehydrogenase, NAD binding domain
- UBCc_UEV
- enzyme
- protein binding
- lactate/malate dehydrogenase, alpha/beta C-terminal domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- exosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Uevld gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein modification process
- protein transport
- endosome to lysosome transport
- carboxylic acid metabolic process
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- ESCRT I complex
Molecular Function
What the gene product does at the molecular level
- oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
- ubiquitin binding