Ctrc Gene Summary [Rat]
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to act upstream of or within intracellular calcium ion homeostasis. Orthologous to human CTRC (chymotrypsin C). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ctrc |
| Official Name | chymotrypsin C [Source:RGD Symbol;Acc:1308379] |
| Ensembl ID | ENSRNOG00000013745 |
| Bio databases IDs | |
| Aliases | chymotrypsin C |
| Synonyms | 1810044E12RIK, chymotrypsin C, CLCR, ELA4 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ctrc often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- serine endopeptidase
- peptidase
- protein binding
Pathways
Biological processes and signaling networks where the Ctrc gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- chronic pancreatitis
- COVID-19
- hereditary pancreatitis
- hereditary chronic pancreatitis
- idiopathic chronic pancreatitis
- covid-19 death
- alcoholic pancreatitis
- non-alcoholic chronic pancreatitis
role in cell
- homeostasis in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ctrc gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
- cellular calcium ion homeostasis
Molecular Function
What the gene product does at the molecular level
- protein binding
- serine-type endopeptidase activity
- peptidase activity