CTRC Gene Summary [Human]

This gene encodes a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
CTRC
Official Name
chymotrypsin C [Source:HGNC Symbol;Acc:HGNC:2523]
Ensembl ID
ENSG00000162438
Bio databases IDs NCBI: 11330 Ensembl: ENSG00000162438
Aliases chymotrypsin C, elastase 4, caldecrin, chymotrypsinogen C
Synonyms 1810044E12RIK, chymotrypsin C, CLCR, ELA4
Species
Human, Homo sapiens
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CTRC often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Trypsin-like serine protease
  • trypsin
  • Tryp_SPc
  • serine endopeptidase
  • peptidase
  • protein binding

Pathways

Biological processes and signaling networks where the CTRC gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • chronic pancreatitis
  • COVID-19
  • hereditary pancreatitis
  • hereditary chronic pancreatitis
  • idiopathic chronic pancreatitis
  • covid-19 death
  • alcoholic pancreatitis
  • non-alcoholic chronic pancreatitis
regulates
role in cell
  • homeostasis in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human CTRC gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteolysis
  • cellular calcium ion homeostasis

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • serine-type endopeptidase activity
  • peptidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.