Cep78 Gene Summary [Rat]
Predicted to be involved in several processes, including flagellated sperm motility; negative regulation of protein ubiquitination; and protein localization to organelle. Predicted to be active in centriole; centrosome; and ciliary basal body. Orthologous to human CEP78 (centrosomal protein 78). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cep78 |
| Official Name | centrosomal protein 78 [Source:RGD Symbol;Acc:620464] |
| Ensembl ID | ENSRNOG00000014041 |
| Bio databases IDs | |
| Aliases | centrosomal protein 78 |
| Synonyms | 5730599I05Rik, C9orf81, centrosomal protein 78, CRDHL, D030027P05, IP63 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cep78 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Leucine rich repeat, ribonuclease inhibitor type
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- retinal dystrophy
- cone-rod dystrophy and hearing loss 1
- small cell lung cancer
- androgenic alopecia
- cone-rod dystrophy and hearing loss
- cone-rod dystrophy
- Moyamoya disease
regulated by
regulates
role in cell
- motility
- organization
- ubiquitination in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- basal bodies
- centrosome
- centriole
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cep78 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- centrosome
- centriole
- cilium basal body
- cytosol