Qrfpr Gene Summary [Rat]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and cellular response to hormone stimulus. Predicted to be located in non-motile cilium. Predicted to be active in plasma membrane. Orthologous to human QRFPR (pyroglutamylated RFamide peptide receptor). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Qrfpr
Official Name
pyroglutamylated RFamide peptide receptor [Source:RGD Symbol;Acc:728380]
Ensembl ID
ENSRNOG00000014414
Bio databases IDs NCBI: 310327 Ensembl: ENSRNOG00000014414
Aliases pyroglutamylated RFamide peptide receptor
Synonyms AQ27, GPR103, pyroglutamylated RFamide peptide receptor, SP9155
Species
Rat, Rattus norvegicus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Qrfpr often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • Cholecystokinin A receptor, N-terminal
  • 7 transmembrane receptor (rhodopsin family)
  • protein binding
  • seven-transmembrane G protein-coupled receptor superfamily

Pathways

Biological processes and signaling networks where the Qrfpr gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Ewing sarcoma
  • osteosarcomagenesis
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • membrane fraction
  • non-motile cilium
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Qrfpr gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • neuropeptide signaling pathway
  • G-protein coupled receptor signaling pathway
  • cellular response to hormone stimulus

Cellular Component

Where in the cell the gene product is active
  • membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • G-protein coupled receptor activity
  • protein binding
  • peptide binding
  • neuropeptide Y receptor activity

Gene-Specific Assays for Results You Can Trust

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