QRFPR
QRFPR Gene Summary
Enables G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway. Predicted to be located in non-motile cilium. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | QRFPR |
| Official Name | pyroglutamylated RFamide peptide receptor [Source:HGNC Symbol;Acc:HGNC:15565] |
| Ensembl ID | ENSG00000186867 |
| Bio databases IDs | |
| Aliases | pyroglutamylated RFamide peptide receptor, peptide P518 receptor |
| Synonyms | AQ27,GPR103,pyroglutamylated RFamide peptide receptor,SP9155 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- Cholecystokinin A receptor, N-terminal
- 7 transmembrane receptor (rhodopsin family)
- protein binding
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the QRFPR gene plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
- GJA8
- PTEN
- QRFP
- NTM
disease
- Ewing sarcoma
- osteosarcomagenesis
regulated by
- QRFP
- Orf3
- KAT5
regulates
role in cell
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- membrane fraction
- non-motile cilium
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the QRFPR gene, providing context for its role in the cell.
BIOLOGICAL PROCESS
Functions and activities the gene product is involved in
- neuropeptide signaling pathway
- G-protein coupled receptor signaling pathway
- cellular response to hormone stimulus
CELLULAR COMPONENT
Where in the cell the gene product is active
- membrane
- plasma membrane
MOLECULAR FUNCTION
What the gene product does at the molecular level
- G-protein coupled receptor activity
- protein binding
- peptide binding
- neuropeptide Y receptor activity