Zc3h4 Gene Summary [Rat]

Predicted to enable RNA binding activity and promoter-specific chromatin binding activity. Predicted to be involved in RNA catabolic process and negative regulation of DNA-templated transcription. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human ZC3H4 (zinc finger CCCH-type containing 4). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Zc3h4
Official Name
zinc finger CCCH-type containing 4 [Source:RGD Symbol;Acc:1596943]
Ensembl ID
ENSRNOG00000015229
Bio databases IDs NCBI: 678741 Ensembl: ENSRNOG00000015229
Aliases zinc finger CCCH-type containing 4
Synonyms Bwq1, C19orf7, Gm768, Kiaa1064-hp, LOC108349211, zinc finger CCCH-type containing 4
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Zc3h4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • zinc finger
  • transcription regulator
  • CCCH-type zinc finger
  • chromatin binding
  • Zinc finger C-x8-C-x5-C-x3-H type (and similar)
  • protein binding
  • zinc finger domain
  • RNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • metabolic syndrome X
regulated by
  • H1-1
  • H1-6
role in cell
  • cohesion in
  • capivasertib resistance
  • cohesion

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Zc3h4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • negative regulation of transcription elongation, DNA-dependent
  • transcription termination, DNA-dependent
  • nuclear RNA surveillance

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytosol
  • chromosome
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.