Zc3h4 Gene Summary [Mouse]
Enables chromatin binding activity. Involved in RNA catabolic process and negative regulation of DNA-templated transcription. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including early conceptus; oocyte; retina; and telencephalon. Orthologous to human ZC3H4 (zinc finger CCCH-type containing 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Zc3h4 |
| Official Name | zinc finger CCCH-type containing 4 [Source:MGI Symbol;Acc:MGI:2682314] |
| Ensembl ID | ENSMUSG00000059273 |
| Bio databases IDs | |
| Aliases | zinc finger CCCH-type containing 4 |
| Synonyms | Bwq1, C19orf7, Gm768, Kiaa1064-hp, LOC108349211, zinc finger CCCH-type containing 4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zc3h4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- zinc finger
- transcription regulator
- CCCH-type zinc finger
- chromatin binding
- Zinc finger C-x8-C-x5-C-x3-H type (and similar)
- protein binding
- zinc finger domain
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zc3h4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription elongation, DNA-dependent
- transcription termination, DNA-dependent
- nuclear RNA surveillance
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
- chromosome
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- metal ion binding