Ifrd2 Gene Summary [Rat]
Predicted to enable ribosome binding activity and translation repressor activity. Predicted to be involved in negative regulation of translation. Predicted to act upstream of or within several processes, including Wnt signaling pathway; adipose tissue development; and fat cell differentiation. Orthologous to human IFRD2 (interferon related developmental regulator 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ifrd2 |
| Official Name | interferon-related developmental regulator 2 [Source:RGD Symbol;Acc:1310222] |
| Ensembl ID | ENSRNOG00000016150 |
| Bio databases IDs | |
| Aliases | interferon-related developmental regulator 2 |
| Synonyms | 1810034A24Rik, IFNRP, interferon-related developmental regulator 2, SKMc15, SM15 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ifrd2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- translation repressor
- ribosome binding
- protein binding
- Interferon-related developmental regulator (IFRD)
- Interferon-related protein conserved region
- translation regulator
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ifrd2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of translation
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein binding
- ribosome binding
- translation repressor activity