Fam92a Gene Summary [Rat]
Predicted to enable phospholipid binding activity. Predicted to be involved in several processes, including inner mitochondrial membrane organization; membrane tubulation; and positive regulation of smoothened signaling pathway. Predicted to be located in several cellular components, including centriole; ciliary base; and mitochondrial crista. Predicted to be active in ciliary basal body and ciliary transition zone. Orthologous to human CIBAR1 (CBY1 interacting BAR domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fam92a |
| Official Name | family with sequence similarity 92 member A [Source:RGD Symbol;Acc:1310681] |
| Ensembl ID | ENSRNOG00000016338 |
| Bio databases IDs | |
| Aliases | family with sequence similarity 92 member A |
| Synonyms | 6720467C03Rik, BARMR1, CBY1 interacting BAR domain containing 1, FAM92A, FAM92A1, PAPA9, RGD1310681 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fam92a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phospholipid binding
- Vps5 C terminal like
- protein binding
- Bin/Amphiphysin/Rvs domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ciliary transition zone
- sperm annulus
- cilia
- Nucleus
- basal bodies
- centriole
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Fam92a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- membrane organization
- cilium morphogenesis
- positive regulation of smoothened signaling pathway
- limb morphogenesis
- inner mitochondrial membrane organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- mitochondrial crista
- centriole
- cilium basal body
- mitochondrion
- ciliary transition zone
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- phospholipid binding