LOC361646 Gene Summary [Rat]

Predicted to act upstream of or within cerebrospinal fluid circulation. Predicted to be located in microtubule organizing center; nucleoplasm; and plasma membrane. Human ortholog(s) of this gene implicated in Joubert syndrome 26. Orthologous to human KATNIP (katanin interacting protein). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
LOC361646
Official Name
similar to K04F10.2 [Source:RGD Symbol;Acc:1595846]
Ensembl ID
ENSRNOG00000016635
Bio databases IDs NCBI: 361646 Ensembl: ENSRNOG00000016635
Aliases similar to K04F10.2
Synonyms D430042O09Rik, JBTS26, katanin interacting protein, KIAA0556, RGD1307324
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Loc361646 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Domain of unknown function (DUF4457)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • psoriasis
  • idiopathic scoliosis
  • Joubert syndrome type 26
  • Joubert syndrome type 1
  • myopia
  • ciliopathy
regulated by
  • levodopa
role in cell
  • crizotinib sensitivity

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • cilia
  • Plasma Membrane
  • basal bodies
  • centrosome
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Loc361646 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • cytoskeleton
  • cytoplasm
  • cell projection

Gene-Specific Assays for Results You Can Trust

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