Nhlrc2 Gene Summary [Rat]

Predicted to be located in cytosol. Orthologous to human NHLRC2 (NHL repeat containing 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Nhlrc2
Official Name
NHL repeat containing 2 [Source:RGD Symbol;Acc:1307348]
Ensembl ID
ENSRNOG00000016948
Bio databases IDs NCBI: 307986 Ensembl: ENSRNOG00000016948
Aliases NHL repeat containing 2
Synonyms 1200003G01RIK, AI835049, AW496455, FINCA, NHL repeat containing 2
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nhlrc2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • NHL repeat
  • Thioredoxin-like
  • Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
  • AhpC/TSA family
  • enzyme
  • protein binding
  • NHL repeat unit of beta-propeller proteins
  • Low-density lipoprotein-receptor YWTD domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • fibrosis, neurodegeneration and cerebral angiomatosis
regulates
  • zymosan
  • RHOA
  • Myelin
role in cell
  • activation in
  • phagocytosis
  • phagocytosis by
  • loss in
  • loss

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Extracellular Space
  • cytosol
  • alpha granules

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Nhlrc2 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • platelet alpha granule lumen
  • cytosol
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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