Lcn8 Gene Summary [Rat]

Predicted to enable small molecule binding activity. Predicted to act upstream of or within response to hormone. Predicted to be located in extracellular region. Orthologous to human LCN8 (lipocalin 8). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Lcn8
Official Name
lipocalin 8 [Source:RGD Symbol;Acc:1306747]
Ensembl ID
ENSRNOG00000017161
Bio databases IDs NCBI: 366008 Ensembl: ENSRNOG00000017161
Aliases lipocalin 8
Synonyms 9230106L18Rik, EP17, LCN5, lipocalin 8, LOC138307, mEP17, RGD1306747
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Lcn8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • lipocalin/cytosolic fatty acid-binding protein family
  • Lipocalin / cytosolic fatty-acid binding protein family
  • transporter

Pathways

Biological processes and signaling networks where the Lcn8 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • LHCGR
  • regulatory T lymphocytes
  • busulfan
  • testosterone
  • 1,25-dihydroxyvitamin D

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • apical cell surfaces

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Lcn8 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • response to hormone stimulus

Cellular Component

Where in the cell the gene product is active
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • small molecule binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.