Otoa Gene Summary [Rat]

Predicted to be involved in cell-matrix adhesion. Predicted to act upstream of or within sensory perception of sound and transmission of nerve impulse. Predicted to be located in apical plasma membrane. Predicted to be active in cell surface. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 22. Orthologous to human OTOA (otoancorin). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Otoa
Official Name
otoancorin [Source:RGD Symbol;Acc:1562741]
Ensembl ID
ENSRNOG00000017487
Bio databases IDs NCBI: 499260 Ensembl: ENSRNOG00000017487
Aliases otoancorin
Synonyms CT108, DFNB22, otoancorin, RGD1562741
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • major depression
  • autosomal recessive deafness type 22
  • autosomal recessive deafness
  • familial nonsyndromic hearing impairment
  • parasitosis
  • autosomal recessive deafness type 7
regulated by
role in cell
  • adhesion
  • transmission

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • Plasma Membrane
  • apical membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Otoa gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sensory perception of sound
  • cell-matrix adhesion
  • transmission of nerve impulse

Cellular Component

Where in the cell the gene product is active
  • extracellular region
  • plasma membrane
  • apical plasma membrane
  • cell surface

Gene-Specific Assays for Results You Can Trust

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