Otoa Gene Summary [Mouse]
Acts upstream of or within cell-matrix adhesion; sensory perception of sound; and transmission of nerve impulse. Located in apical plasma membrane. Is expressed in inner ear; male reproductive gland or organ; small intestine; and trachea. Used to study autosomal recessive nonsyndromic deafness 22. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 22. Orthologous to human OTOA (otoancorin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Otoa |
| Official Name | otoancorin [Source:MGI Symbol;Acc:MGI:2149209] |
| Ensembl ID | ENSMUSG00000034990 |
| Bio databases IDs | |
| Aliases | otoancorin |
| Synonyms | CT108, DFNB22, otoancorin, RGD1562741 |
| Species | Mouse, Mus musculus |
| Orthologies |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Plasma Membrane
- apical membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Otoa gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sensory perception of sound
- cell-matrix adhesion
- transmission of nerve impulse
Cellular Component
Where in the cell the gene product is active
- extracellular region
- plasma membrane
- apical plasma membrane
- cell surface