Gfod2 Gene Summary [Rat]

Predicted to enable nucleotide binding activity and oxidoreductase activity. Predicted to be involved in extracellular matrix organization. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Gfod2
Official Name
glucose-fructose oxidoreductase domain containing 2 [Source:RGD Symbol;Acc:1311198]
Ensembl ID
ENSRNOG00000017953
Bio databases IDs NCBI: 307801 Ensembl: ENSRNOG00000017953
Aliases glucose-fructose oxidoreductase domain containing 2
Synonyms 5730466C23Rik, Gfo/Idh/MocA-like oxidoreductase domain containing 2, glucose-fructose oxidoreductase domain containing 2, MGC11335, RGD1311198
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gfod2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Rossmann-fold NAD(P)(+)-binding proteins
  • Oxidoreductase family, C-terminal alpha/beta domain
  • Oxidoreductase family, NAD-binding Rossmann fold
  • enzyme

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • male pattern hair loss
regulated by
role in cell
  • organization

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • extracellular matrix

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Gfod2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • extracellular matrix organization

Cellular Component

Where in the cell the gene product is active
  • extracellular matrix
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • nucleotide binding
  • oxidoreductase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.