Gfod2 Gene Summary [Mouse]
Predicted to enable nucleotide binding activity and oxidoreductase activity. Acts upstream of or within extracellular matrix organization. Located in extracellular matrix. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and respiratory system. Orthologous to human GFOD2 (Gfo/Idh/MocA-like oxidoreductase domain containing 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gfod2 |
| Official Name | glucose-fructose oxidoreductase domain containing 2 [Source:MGI Symbol;Acc:MGI:1917825] |
| Ensembl ID | ENSMUSG00000013150 |
| Bio databases IDs | |
| Aliases | glucose-fructose oxidoreductase domain containing 2 |
| Synonyms | 5730466C23Rik, Gfo/Idh/MocA-like oxidoreductase domain containing 2, glucose-fructose oxidoreductase domain containing 2, MGC11335, RGD1311198 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gfod2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rossmann-fold NAD(P)(+)-binding proteins
- Oxidoreductase family, C-terminal alpha/beta domain
- Oxidoreductase family, NAD-binding Rossmann fold
- enzyme
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- extracellular matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gfod2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- extracellular matrix organization
Cellular Component
Where in the cell the gene product is active
- extracellular matrix
- extracellular region
Molecular Function
What the gene product does at the molecular level
- nucleotide binding
- oxidoreductase activity