Ppp6r1 Gene Summary [Rat]

Predicted to enable protein phosphatase regulator activity and small GTPase binding activity. Predicted to be located in cytosol. Orthologous to human PPP6R1 (protein phosphatase 6 regulatory subunit 1). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Ppp6r1
Official Name
protein phosphatase 6, regulatory subunit 1 [Source:RGD Symbol;Acc:1311409]
Ensembl ID
ENSRNOG00000018090
Bio databases IDs NCBI: 361502 Ensembl: ENSRNOG00000018090
Aliases protein phosphatase 6, regulatory subunit 1
Synonyms 2010309P17Rik, B430201G11Rik, D030074N20Rik, KIAA1115, mKIAA1115, PP6R1, protein phosphatase 6 regulatory subunit 1, protein phosphatase 6, regulatory subunit 1, RGD1311409, SAP190, SAPS1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ppp6r1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SIT4 phosphatase-associated protein
  • protein phosphatase binding
  • protein phosphatase regulator
  • enzyme binding
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • localized cutaneous leishmaniasis
regulated by
  • hematopoietic progenitor cells
  • T lymphocytes
regulates
role in cell
  • apoptosis
  • phagocytosis by
  • degradation in
  • phagocytosis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Ppp6r1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of phosphoprotein phosphatase activity

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • protein phosphatase binding
  • small GTPase binding
  • protein phosphatase regulator activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.