C2cd5 Gene Summary [Rat]

Predicted to enable calcium ion binding activity and calcium-dependent phospholipid binding activity. Predicted to be involved in several processes, including insulin receptor signaling pathway; positive regulation of protein targeting to membrane; and positive regulation of transport. Predicted to act upstream of or within positive regulation of D-glucose import and vesicle fusion. Predicted to be located in several cellular components, including centriolar satellite; cytoplasmic vesicle membrane; and ruffle membrane. Predicted to be active in plasma membrane. Orthologous to human C2CD5 (C2 calcium dependent domain containing 5). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
C2cd5
Official Name
C2 calcium-dependent domain containing 5 [Source:RGD Symbol;Acc:1304592]
Ensembl ID
ENSRNOG00000014382
Bio databases IDs NCBI: 362461 Ensembl: ENSRNOG00000014382
Aliases C2 calcium-dependent domain containing 5
Synonyms 5730419I09Rik, C030008B15Rik, C2 calcium-dependent domain containing 5, CDP138, KIAA0528, RGD1304592
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat C2cd5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • calcium ion binding
  • calcium-dependent phospholipid binding
  • protein binding
  • Protein kinase C conserved region 2 (CalB)
  • Serine Proline motif
  • C2 domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • obesity
regulated by
  • F2
  • T lymphocytes
  • hematopoietic progenitor cells
  • WPMY-1 cells
regulates
role in cell
  • fusion

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytoplasmic vesicle membrane
  • cell cortex
  • Plasma Membrane
  • centrosome
  • cytosol
  • membrane ruffles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat C2cd5 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of glucose transport
  • positive regulation of protein targeting to membrane
  • positive regulation of vesicle fusion
  • insulin receptor signaling pathway
  • intracellular protein transmembrane transport
  • protein localization in plasma membrane

Cellular Component

Where in the cell the gene product is active
  • cytoplasmic vesicle membrane
  • centriolar satellite
  • cell cortex
  • cytosol
  • ruffle membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • calcium ion binding
  • calcium-dependent phospholipid binding

Gene-Specific Assays for Results You Can Trust

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