Leng8 Gene Summary [Rat]

Predicted to be active in nucleus. Orthologous to human LENG8 (leukocyte receptor cluster member 8). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Leng8
Official Name
leukocyte receptor cluster member 8 [Source:RGD Symbol;Acc:1306180]
Ensembl ID
ENSRNOG00000018642
Bio databases IDs NCBI: 361506 Ensembl: ENSRNOG00000018642
Aliases leukocyte receptor cluster member 8
Synonyms leukocyte receptor cluster (LRC) member 8, leukocyte receptor cluster member 8, pp13842
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Leng8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SAC3/GANP family
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • paroxysmal nocturnal hemoglobinuria
regulated by
  • TAFAZZIN
  • pidnarulex
  • lipopolysaccharide
  • KDM4C
  • MYC
  • WNT3A
  • laduviglusib
  • 3,5-dihydroxyphenylglycine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Leng8 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • macromolecular complex

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.