Snapc4 Gene Summary [Rat]
Predicted to enable RNA polymerase II general transcription initiation factor activity; RNA polymerase III general transcription initiation factor activity; and RNA polymerase III type 3 promoter sequence-specific DNA binding activity. Predicted to contribute to RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in snRNA transcription by RNA polymerase II and snRNA transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of snRNA-activating protein complex. Orthologous to human SNAPC4 (small nuclear RNA activating complex polypeptide 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Snapc4 |
| Official Name | small nuclear RNA activating complex, polypeptide 4 [Source:RGD Symbol;Acc:1309048] |
| Ensembl ID | ENSRNOG00000018845 |
| Bio databases IDs | |
| Aliases | small nuclear RNA activating complex, polypeptide 4 |
| Synonyms | 5730436L13RIK, NEDRSO, PTFalpha, small nuclear RNA activating complex polypeptide 4, small nuclear RNA activating complex, polypeptide 4, SNAP190 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Snapc4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SANT
- Family of unknown function (DUF5585)
- transcription regulator
- SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
- Myb-like DNA-binding domain
- protein binding
- general RNA polymerase II transcription factor
- DNA binding
- Myb repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neurodevelopmental disorder with motor regression, progressive spastic paraplegia, and oromotor dysfunction
- Crohn disease
- ulcerative colitis
- inflammatory bowel disease
regulates
- RNU2-1
- RNU1-4
- Rnu6
- RN7SK
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Snapc4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- snRNA transcription from RNA polymerase II promoter
- snRNA transcription from RNA polymerase III promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- snRNA-activating protein complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- general RNA polymerase II transcription factor activity
- RNA polymerase II core promoter proximal region sequence-specific DNA binding
- RNA polymerase III type 3 promoter sequence-specific DNA binding
- core RNA polymerase III binding transcription factor activity