Ino80e Gene Summary [Rat]

Predicted to be involved in several processes, including chromatin remodeling; regulation of chromosome organization; and regulation of nucleobase-containing compound metabolic process. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of Ino80 complex. Orthologous to human INO80E (INO80 complex subunit E). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ino80e
Official Name
INO80 complex subunit E [Source:RGD Symbol;Acc:1359572]
Ensembl ID
ENSRNOG00000019960
Bio databases IDs NCBI: 293494 Ensembl: ENSRNOG00000019960
Aliases INO80 complex subunit E
Synonyms Ccdc85, CCDC95, INO80 complex subunit E
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ino80e often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by
  • levodopa
role in cell
  • cell cycle progression
  • organization
  • remodeling

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Ino80e gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of DNA repair
  • DNA repair
  • regulation of chromosome organization
  • regulation of DNA strand elongation
  • regulation of DNA repair
  • DNA recombination
  • regulation of embryonic development
  • telomere maintenance
  • regulation of DNA replication
  • chromatin remodeling
  • positive regulation of transcription, DNA-dependent
  • regulation of cell cycle

Cellular Component

Where in the cell the gene product is active
  • Ino80 complex
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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