INO80E Gene Summary [Human]
Predicted to be involved in DNA recombination; DNA repair; and chromatin remodeling. Located in nucleolus and nucleoplasm. Part of Ino80 complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | INO80E |
| Official Name | INO80 complex subunit E [Source:HGNC Symbol;Acc:HGNC:26905] |
| Ensembl ID | ENSG00000169592 |
| Bio databases IDs | |
| Aliases | INO80 complex subunit E |
| Synonyms | Ccdc85, CCDC95, INO80 complex subunit E |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human INO80E often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human INO80E gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of DNA repair
- DNA repair
- regulation of chromosome organization
- regulation of DNA strand elongation
- regulation of DNA repair
- DNA recombination
- regulation of embryonic development
- telomere maintenance
- regulation of DNA replication
- chromatin remodeling
- positive regulation of transcription, DNA-dependent
- regulation of cell cycle
Cellular Component
Where in the cell the gene product is active
- Ino80 complex
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding