Sntb2 Gene Summary [Rat]
Predicted to enable actin binding activity and structural molecule activity. Predicted to be located in several cellular components, including Golgi apparatus; microtubule organizing center; and nucleoplasm. Predicted to be part of dystrophin-associated glycoprotein complex. Predicted to be active in synapse. Orthologous to human SNTB2 (syntrophin beta 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sntb2 |
| Official Name | syntrophin, beta 2 [Source:RGD Symbol;Acc:1592340] |
| Ensembl ID | ENSRNOG00000020344 |
| Bio databases IDs | |
| Aliases | syntrophin, beta 2 |
| Synonyms | D16S2531E, EST25263, Snt2, SNT2B2, SNT3, SNTL, syntrophin, basic 2, Syntrophin beta2, syntrophin, beta 2, SYNTROPHIN beta 2 A, syntrophin β 2, syntrophin, β 2, SYNTROPHIN β 2 A |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Sntb2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain present in PSD-95, Dlg, and ZO-1/2
- canonical PDZ domain
- PH domain
- protein binding
- phosphotyrosine binding domain
- Pleckstrin homology-like domain
- PDZ domain
Pathways
Biological processes and signaling networks where the Sntb2 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- cellular membrane
- basal bodies
- centrosome
- Golgi Apparatus
- cytosol
- nucleoplasm
- acrosome
- neuromuscular junctions
- synapse
- sarcolemma
- secretory granules
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Sntb2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- Golgi apparatus
- synapse
- plasma membrane
- intracellular
- nucleoplasm
- microtubule
- transport vesicle membrane
- focal adhesion
- cytoplasm
- membrane
- dystrophin-associated glycoprotein complex
- macromolecular complex
Molecular Function
What the gene product does at the molecular level
- calmodulin binding
- protein binding
- RNA binding
- actin binding
- structural molecule activity