Mau2 Gene Summary [Rat]
Predicted to enable cohesin loader activity. Predicted to be involved in maintenance of mitotic sister chromatid cohesion. Predicted to be located in nuclear body. Predicted to be part of Scc2-Scc4 cohesin loading complex. Predicted to be active in chromatin. Orthologous to human MAU2 (MAU2 sister chromatid cohesion factor). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mau2 |
| Official Name | MAU2 sister chromatid cohesion factor [Source:RGD Symbol;Acc:1308759] |
| Ensembl ID | ENSRNOG00000020526 |
| Bio databases IDs | |
| Aliases | MAU2 sister chromatid cohesion factor |
| Synonyms | 9130404D08Rik, A930019L04Rik, Gm7730, KIAA0892, MAU2L, MAU2 sister chromatid cohesion factor, mKIAA0892, RGD1308759, RP24-335A22.6, SCC4 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mau2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cohesin loading factor
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nuclear bodies
- chromatin
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Mau2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- maintenance of mitotic sister chromatid cohesion
- mitotic sister chromatid cohesion
- chromosome segregation
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear body
- chromatin
- nucleoplasm
- SMC loading complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- double-stranded DNA binding