Icam5 Gene Summary [Rat]
Predicted to enable integrin binding activity. Predicted to be involved in cell adhesion and regulation of synapse assembly. Predicted to act upstream of or within phagocytosis. Predicted to be active in glutamatergic synapse; plasma membrane; and postsynapse. Orthologous to human ICAM5 (intercellular adhesion molecule 5). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Icam5 |
| Official Name | intercellular adhesion molecule 5 [Source:RGD Symbol;Acc:1305039] |
| Ensembl ID | ENSRNOG00000020694 |
| Bio databases IDs | |
| Aliases | intercellular adhesion molecule 5 |
| Synonyms | intercellular adhesion molecule 5 |
| Species | Rat, Rattus norvegicus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Icam5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Intercellular adhesion molecule (ICAM), N-terminal domain
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin I-set domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- glutaminergic synapse
- postsynaptic region
- dendritic spines
- dendrites