Elp6 Gene Summary [Rat]
Predicted to be involved in positive regulation of cell migration. Predicted to act upstream of or within several processes, including autophagosome maturation; gene expression; and homeostasis of number of retina cells. Predicted to be located in cytosol and nucleus. Predicted to be part of elongator holoenzyme complex. Orthologous to human ELP6 (elongator acetyltransferase complex subunit 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Elp6 |
| Official Name | elongator acetyltransferase complex subunit 6 [Source:RGD Symbol;Acc:1305478] |
| Ensembl ID | ENSRNOG00000020847 |
| Bio databases IDs | |
| Aliases | elongator acetyltransferase complex subunit 6 |
| Synonyms | 2610001P13Rik, 2610002I17Rik, C3orf75, elongator acetyltransferase complex subunit 6, RGD1305478, TMEM103 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Elp6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Elongation complex protein 6
- protein binding
- P-loop containing Nucleoside Triphosphate Hydrolases
Pathways
Biological processes and signaling networks where the Elp6 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Crohn disease
- developmental delay, epilepsy, intellectual disability, and motor dysfunction
- motor dysfunction
- tremor
regulated by
- 2-amino-5-phosphonovaleric acid
regulates
- histone H3
- histone H4
role in cell
- apoptosis
- differentiation
- migration
- fusion
- autophagy by
- response by
- branching in
- translation in
- length
- branching
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Elp6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of translation
- tRNA wobble uridine modification
- positive regulation of cell migration
Cellular Component
Where in the cell the gene product is active
- nucleus
- Elongator holoenzyme complex
- cytosol