Bola3

Predicted to be involved in protein maturation. Predicted to act upstream of or within several processes, including energy homeostasis; protein lipoylation; and response to lipoic acid. Predicted to be located in cytosol and nuclear body. Predicted to be part of iron-sulfur cluster assembly complex. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 2. Orthologous to human BOLA3 (bolA family member 3). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Bola3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Bola3 gene, providing context for its role in the cell.