Bhlha9 Gene Summary [Rat]

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and protein heterodimerization activity. Predicted to be involved in developmental process and regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Orthologous to human BHLHA9 (basic helix-loop-helix family member a9). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Bhlha9
Official Name
basic helix-loop-helix family, member a9 [Source:RGD Symbol;Acc:1311234]
Ensembl ID
ENSRNOG00000022232
Bio databases IDs NCBI: 363656 Ensembl: ENSRNOG00000022232
Aliases basic helix-loop-helix family, member a9
Synonyms A830053O21Rik, basic helix-loop-helix family member a9, basic helix-loop-helix family, member a9, BHLHF42, CCSPD, Fingerin, MSSD, RGD1311234
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Bhlha9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RNA polymerase II transcription factor activity, sequence-specific DNA binding
  • transcription regulator
  • basic Helix Loop Helix (bHLH) domain superfamily
  • helix loop helix domain
  • protein binding
  • Helix-loop-helix DNA-binding domain
  • protein heterodimerization

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • complex camptosynpolydactyly
  • mesoaxial synostotic syndactyly with phalangeal reduction
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • chromatin

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Bhlha9 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • developmental process
  • regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • chromatin

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • protein heterodimerization activity
  • RNA polymerase II regulatory region sequence-specific DNA binding
  • sequence-specific DNA binding RNA polymerase II transcription factor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.