Rasef Gene Summary [Rat]
Predicted to enable GTPase activity; guanyl ribonucleotide binding activity; and identical protein binding activity. Predicted to be involved in vesicle-mediated transport. Predicted to be active in cytosol and perinuclear region of cytoplasm. Orthologous to human RASEF (RAS and EF-hand domain containing). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rasef |
| Official Name | RAS and EF hand domain containing [Source:RGD Symbol;Acc:1306418] |
| Ensembl ID | ENSRNOG00000024190 |
| Bio databases IDs | |
| Aliases | RAS and EF hand domain containing |
| Synonyms | LOC683719, RAB45, RAS and EF-hand domain containing, TSG |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rasef often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ciliary protein causing Leber congenital amaurosis disease
- EF-hand domain pair
- Small GTPase of the Ras superfamily (ill-defined subfamily)
- Ras family
- 50S ribosome-binding GTPase
- EFh
- identical protein binding
- Ras subfamily of RAS small GTPases
- GTP binding
- small GTP-binding protein domain
- GDP binding
- Rab subfamily of small GTPases
- Ras of Complex, Roc, domain of DAPkinase
- ADP-ribosylation factor
- Rho (Ras homology) subfamily of Ras-like small GTPases
- P-loop containing Nucleoside Triphosphate Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear region
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rasef gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- vesicle-mediated transport
Cellular Component
Where in the cell the gene product is active
- perinuclear region of cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- GTP binding
- identical protein binding
- GTPase activity
- calcium ion binding
- GDP binding