Oc90 Gene Summary [Rat]

Predicted to enable several functions, including calcium ion binding activity; calcium-dependent phospholipase A2 activity; and phospholipid binding activity. Predicted to be involved in otolith mineralization; phosphatidylcholine metabolic process; and phosphatidylglycerol metabolic process. Predicted to be located in extracellular region and membrane. Predicted to be active in extracellular matrix. Orthologous to human OC90 (otoconin 90). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Oc90
Official Name
otoconin 90 [Source:RGD Symbol;Acc:1593441]
Ensembl ID
ENSRNOG00000025516
Bio databases IDs NCBI: 690625 Ensembl: ENSRNOG00000025516
Aliases otoconin 90
Synonyms LOC100911171, LOC102546467, LOC684671, oc95, Ocn-95, Otoconin 90, PLA2L, Pla2ll
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Oc90 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • calcium ion binding
  • enzyme
  • protein binding
  • structural molecule
  • phospholipase A2
  • PLA2_like

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • proliferative diabetic retinopathy
regulated by
  • U0126
  • HTT
  • PTH
  • H89
  • bisindolylmaleimide I
role in cell
  • calcification in
  • calcification

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • extracellular matrix

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Oc90 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • phosphatidylcholine metabolic process
  • arachidonic acid secretion
  • otolith mineralization
  • lipid catabolic process
  • phospholipid metabolic process

Cellular Component

Where in the cell the gene product is active
  • extracellular matrix
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • calcium-dependent phospholipase A2 activity
  • calcium ion binding
  • structural molecule activity
  • phospholipid binding

Gene-Specific Assays for Results You Can Trust

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