Afg3l1 Gene Summary [Rat]

Predicted to enable metalloendopeptidase activity. Predicted to be involved in mitochondrial protein processing. Predicted to be part of m-AAA complex. [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Afg3l1
Official Name
AFG3(ATPase family gene 3)-like 1 (S. cerevisiae) [Source:RGD Symbol;Acc:1309722]
Ensembl ID
ENSRNOG00000026994
Bio databases IDs NCBI: 361436 Ensembl: ENSRNOG00000026994
Aliases AFG3(ATPase family gene 3)-like 1 (S. cerevisiae)
Synonyms 1700047G05Rik, 3110061K15Rik, AFG3 (ATPase family gene 3)-like 1, AFG3-like AAA ATPase 1
Species
Rat, Rattus norvegicus
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Afg3l1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • peptidase
  • Peptidase family M41
  • protein binding
  • AAA+ lid domain
  • ATPase
  • AAA domain
  • AAA domain (dynein-related subfamily)
  • ATPase family associated with various cellular activities (AAA)
  • ATP-dependent metalloprotease FtsH
  • FtsH Extracellular
  • P-loop containing Nucleoside Triphosphate Hydrolases
  • ATPases associated with a variety of cellular activities
  • transporter
  • metalloendopeptidase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
role in cell
  • accumulation in
  • formation
  • organization
  • stabilization in
  • maturation in
  • fusion

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial membrane
  • mitochondrial inner membrane

Gene-Specific Assays for Results You Can Trust

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