Ttc7b Gene Summary [Rat]

Predicted to be involved in phosphatidylinositol phosphate biosynthetic process and protein localization to plasma membrane. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Orthologous to human TTC7B (tetratricopeptide repeat domain 7B). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ttc7b
Official Name
tetratricopeptide repeat domain 7B [Source:RGD Symbol;Acc:1305920]
Ensembl ID
ENSRNOG00000027300
Bio databases IDs NCBI: 362768 Ensembl: ENSRNOG00000027300
Aliases tetratricopeptide repeat domain 7B
Synonyms c14 5685, tetratricopeptide repeat domain 7B, TTC7L1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ttc7b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Tetratricopeptide repeat protein 7 N-terminal
  • Tetratricopeptide repeats
  • protein binding
  • tetratricopeptide repeat

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
  • non-insulin-dependent diabetes mellitus
  • streptococcal pharyngitis
  • cutaneous melanoma
  • cutaneous melanoma cancer
regulated by
regulates
  • phosphatidylinositol
role in cell
  • invasion by
  • fitness

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Ttc7b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • phosphatidylinositol phosphorylation
  • protein localization in plasma membrane

Cellular Component

Where in the cell the gene product is active
  • cytosol
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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