Ttc7b Gene Summary [Mouse]
Predicted to be involved in phosphatidylinositol phosphate biosynthetic process and protein localization to plasma membrane. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; liver; and retina nuclear layer. Orthologous to human TTC7B (tetratricopeptide repeat domain 7B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ttc7b |
| Official Name | tetratricopeptide repeat domain 7B [Source:MGI Symbol;Acc:MGI:2144724] |
| Ensembl ID | ENSMUSG00000033530 |
| Bio databases IDs | |
| Aliases | tetratricopeptide repeat domain 7B |
| Synonyms | c14 5685, tetratricopeptide repeat domain 7B, TTC7L1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ttc7b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Tetratricopeptide repeat protein 7 N-terminal
- Tetratricopeptide repeats
- protein binding
- tetratricopeptide repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ttc7b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- phosphatidylinositol phosphorylation
- protein localization in plasma membrane
Cellular Component
Where in the cell the gene product is active
- cytosol
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding