Slc25a2 Gene Summary [Rat]
This intronless gene encodes a protein that localizes to the mitochondrial inner membrane and likely functions as a transporter of small molecules such as ornithine. This gene is located between the protocadherin beta and gamma gene clusters on chromosome 5. [provided by RefSeq, Dec 2014]
Details
| Type | Protein Coding |
| Official Symbol | Slc25a2 |
| Official Name | solute carrier family 25 member 2 [Source:RGD Symbol;Acc:1310667] |
| Ensembl ID | ENSRNOG00000027359 |
| Bio databases IDs | |
| Aliases | solute carrier family 25 member 2 |
| Synonyms | ORC2, ORNT2, solute carrier family 25 member 2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slc25a2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- organic cation transporter
- lysine transporter
- ornithine transporter
- Mitochondrial carrier protein
- L-amino acid transporter
- protein binding
- basic amino acid transporter
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
- N-ethylmaleimide
- spermine
- mercuric chloride
- mersalyl acid
- pyridoxal phosphate
- 4-hydroxymercuribenzenesulfonate
- bathophenanthroline
regulates
- arginine
- L-arginine
- citrulline
- L-lysine
- L-ornithine
- homoarginine
- D-arginine
- D-histidine
- L-histidine
- D-lysine
role in cell
- transport in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Slc25a2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- urea cycle
- ornithine metabolic process
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- L-lysine transmembrane transporter activity
- protein binding
- L-ornithine transmembrane transporter activity
- antiporter activity