Actbl2 Gene Summary [Rat]

Predicted to enable protein kinase binding activity. Predicted to be a structural constituent of postsynaptic actin cytoskeleton. Predicted to be involved in axonogenesis and cell motility. Predicted to be part of NuA4 histone acetyltransferase complex. Predicted to be active in several cellular components, including actin filament; axon; and glutamatergic synapse. Orthologous to human ACTBL2 (actin beta like 2). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Actbl2
Official Name
actin, beta-like 2 [Source:RGD Symbol;Acc:1309504]
Ensembl ID
ENSRNOG00000043292
Bio databases IDs NCBI: 294732 Ensembl: ENSRNOG00000043292
Aliases actin, beta-like 2
Synonyms 4732495G21Rik, ACT, actin beta like 2, actin, beta-like 2, actin β like 2, actin, β-like 2, LOC345651, RGD1309504
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Actbl2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Actin
  • protein binding
  • ASKHA_ATPase-like

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • sickle cell anemia
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • glutaminergic synapse
  • synapse
  • exosomes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Actbl2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell motility
  • axonogenesis

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • NuA4 histone acetyltransferase complex
  • extracellular vesicular exosome
  • cytoplasm
  • membrane
  • actin cytoskeleton
  • actin filament
  • axon

Molecular Function

What the gene product does at the molecular level
  • ATP binding
  • protein kinase binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

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